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Article

A TREML2 missense variant influences specific hippocampal subfield volumes in cognitively normal elderly subjects.

Brain and behavior - 1 Apr 2020

Wang Si-Yu, Xue Xiao, Duan Rui, Gong Peng-Yu, E Yan, Jiang Teng, Zhang Ying-Dong

Abstract excerpt

INTRODUCTION: Triggering receptor expressed on myeloid cells-like transcript 2 gene (TREML2) is a newly identified AD susceptibility gene. Its missense variant rs3747742-C substantially decreases AD risk in both Caucasians and Han Chinese, but the underlying mechanisms remain elusive. In the present study, to uncover the possible mechanisms by which TREML2 rs3747742-C reduces AD risk, we investigated the possible...

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Identifiers

PMID: 32073739
DOI: 10.1002/brb3.1573
PMCID: PMC7177563

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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