Article
Linking Genetics of Brain Changes to Alzheimer's Disease: Sparse Whole Genome Association Scan of Regional MRI Volumes in the ADNI and AddNeuroMed Cohorts.
Journal of Alzheimer's disease : JAD - 1 Jan 2015
Khondoker Mizanur, Newhouse Stephen, Westman Eric, Muehlboeck J-Sebastian, Mecocci Patrizia, Vellas Bruno, Tsolaki Magda, Kłoszewska Iwona, Soininen Hilkka, Lovestone Simon, Dobson Richard, Simmons Andrew
Abstract excerpt
BACKGROUND: Alzheimer's disease (AD) is a highly heritable disease, but until recently few replicated genetic markers have been identified. Markers identified so far are likely to account for only a tiny fraction of the heritability of AD and many more genetic risk alleles are thought to be undis...
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