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Article

Heritable genetic background alters survival and phenotype of Mll-AF9-induced leukemias.

Experimental hematology - 1 Sept 2020

Young Kira, Loberg Matthew A, Eudy Elizabeth, Schwartz Logan S, Mujica Kristina D, Trowbridge Jennifer J

Abstract excerpt

The MLL-AF9 fusion protein occurring as a result of t(9;11) translocation gives rise to pediatric and adult acute leukemias of distinct lineages, including acute lymphoblastic leukemia (ALL), acute myeloid leukemia (AML), and mixed-phenotype acute leukemia (MPAL). The mechanisms underlying how this same fusion protein results in diverse leukemia phenotypes among different individuals are not well understood....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 32768438
DOI: 10.1016/j.exphem.2020.07.012
PMCID: PMC7508790

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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