Advances in the development of animal models of myeloid leukemias.

Abstract excerpt

The ideal in vivo models for studies of leukemia pathogenesis and treatment would have several important features. First, these animals would have phenotypes that are robust and reproducible. Second, these models would reliably develop phenotypes that accurately recapitulate disease observed in the clinic with short latency and high penetrance sufficient for informative preclinical therapeutic studies. Leukemia...

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