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Article

Highly sensitive detection of TERT promoter mutations in recurrent glioblastomas using digital PCR.

Brain tumor pathology - 1 Oct 2020

Miki Shunichiro, Satomi Kaishi, Ohno Makoto, Matsushita Yuko, Kitahara Mai, Miyakita Yasuji, Takahashi Masamichi, Matsuda Masahide, Ishikawa Eiichi, Matsumura Akira, Yoshida Akihiko, Narita Yoshitaka, Ichimura Koichi

Abstract excerpt

Telomerase reverse transcriptase promoter (TERTp) hotspot mutations are the most frequent mutations in primary glioblastomas (GBM). Previous studies have shown that the combination of TERTp and isocitrate dehydrogenase (IDH) status may serve as a useful diagnostic marker for oligodendroglioma and glioblastoma. In oligodendrogliomas, TERTp and IDH mutations, along with the 1p/19q codeletion, usually coexist and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32749624
DOI: 10.1007/s10014-020-00375-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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