Article
Classification based on mutations of TERT promoter and IDH characterizes subtypes in grade II/III gliomas.
Neuro-oncology - 1 Aug 2016
Yang Pei, Cai Jinquan, Yan Wei, Zhang Wei, Wang Yinyan, Chen Baoshi, Li Guilin, Li Shouwei, Wu Chenxing, Yao Kun, Li Wenbin, Peng Xiaoxia, You Yongping, Chen Ling, Jiang Chuanlu, Qiu Xiaoguang, Jiang Tao
Abstract excerpt
BACKGROUND: Grade II and III gliomas have variable clinical behaviors, showing the distinct molecular genetic alterations from glioblastoma (GBM), many of which eventually transform into more aggressive tumors. Since the classifications of grade II/III gliomas based on the genetic alterations have been recently emerging, it is now a trend to include molecular data into the standard diagnostic algorithm of glioma....
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