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Article

Diagnostic implications of TERT promoter mutation status in diffuse gliomas in a routine clinical setting.

Virchows Archiv : an international journal of pathology - 1 Nov 2017

Hewer Ekkehard, Prebil Nadine, Berezowska Sabina, Gutt-Will Marielena, Schucht Philippe, Dettmer Matthias S, Vassella Erik

Abstract excerpt

IDH (isocitrate dehydrogenase) gene mutations are present in most diffuse low-grade gliomas and define the clinico-pathological core of the respective morphologically defined entities. Conversely, according to the 2016 WHO classification, the majority of glioblastomas belong to the IDH-wildtype category, which is defined by exclusion. TERT (telomerase reverse transcriptase gene) promoter mutations have been...

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Source

Identifiers

PMID: 28823044
DOI: 10.1007/s00428-017-2216-x

Genes

TERT
ATRX
MGMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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