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Article

TERT Promoter Mutation Detection in Cell-Free Tumor-Derived DNA in Patients with IDH Wild-Type Glioblastomas: A Pilot Prospective Study.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Nov 2018

Juratli Tareq A, Stasik Sebastian, Zolal Amir, Schuster Caroline, Richter Sven, Daubner Dirk, Juratli Mazen A, Thowe Rachel, Hennig Silke, Makina Meriem, Meinhardt Matthias, Lautenschlaeger Tim, Schackert Gabriele, Krex Dietmar, Thiede Christian

Abstract excerpt

Purpose: We conducted a pilot study to assess the feasibility and the potential implications of detecting TERT promoter (TERTp)-mutant cell-free tumor-derived DNA (tDNA) in the cerebrospinal fluid (CSF) and plasma of glioblastoma patients.Experimental Design: Matched CSF and plasma samples were collected in 60 patients with glial tumors. The CSF collection was obtained during surgery, before any surgical...

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Source

Identifiers

PMID: 29941484
DOI: 10.1158/1078-0432.CCR-17-3717

Genes

TERT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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