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Article

The Place and Prognostic Value of TERT Promoter Mutation in Molecular Classification in Grade II-III Glial Tumors and Primary Glioblastomas.

Turk patoloji dergisi - 1 Jan 2022

Terzi Neslihan Kaya, Yilmaz Ismail, Oz Aysim Buge

Abstract excerpt

OBJECTIVE: Diffuse gliomas, the most common primary malignant brain tumors, have been classified by the World Health Organization as class II-IV gliomas. After 2016, two mutations in the promoter region of the telomerase reverse transcriptase (TERT) gene were identified in addition to the IDH, 1p / 19q, and ATRX status. MATERIAL AND METHOD: We identified 84 patients with grade II-IV glioma with IDH, ATRX, 1p /...

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Share to Brain Neoplasms
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to In Situ Hybridization, Fluorescence

Share to Isocitrate Dehydrogenase

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Share to Promoter Regions, Genetic

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Identifiers

PMID: 34558656
DOI: 10.5146/tjpath.2021.01555
PMCID: PMC9999695

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