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Article

Melanocortin receptor-1 gene polymorphisms and the risk of cutaneous melanoma in a low-risk southern European population.

The Journal of investigative dermatology - 1 Aug 2006

Stratigos Alexander J, Dimisianos Gerasimos, Nikolaou Vasiliki, Poulou Mirto, Sypsa Vana, Stefanaki Irene, Papadopoulos Othon, Polydorou Dorothea, Plaka Michaela, Christofidou Eleftheria, Gogas Helen, Tsoutsos Dimosthenis, Kastana Ourania, Antoniou Christina, Hatzakis Angelos, Kanavakis Emmanouil, Katsambas Andreas D

Abstract excerpt

Individuals with melanocortin 1 receptor (MC1R) gene variants have been shown to carry an increased risk for the development of melanoma. In this study, we investigated the relationship of MC1R gene variants and the risk of melanoma in 123 melanoma patients and 155 control subjects from Greece. The entire MC1R gene was sequenced for polymorphisms and the results were correlated with host factors and pigmentary...

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Identifiers

PMID: 16601669
DOI: 10.1038/sj.jid.5700292

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