Article
Common genetic variants associated with melanoma risk or naevus count in patients with wildtype MC1R melanoma.
The British journal of dermatology - 1 Nov 2022
Calbet-Llopart Neus, Combalia Marc, Kiroglu Anil, Potrony Miriam, Tell-Martí Gemma, Combalia Andrea, Brugues Albert, Podlipnik Sebastian, Carrera Cristina, Puig Susana, Malvehy Josep, Puig-Butillé Joan Anton
Abstract excerpt
BACKGROUND: Hypomorphic MC1R variants are the most prevalent genetic determinants of melanoma risk in the white population. However, the genetic background of patients with wildtype (WT) MC1R melanoma is poorly studied. OBJECTIVES: To analyse the role of candidate common genetic variants on the melanoma risk and naevus count in Spanish patients with WT MC1R melanoma. METHODS: We examined 753 individuals with WT...
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