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Article

Pancreatic Steatosis Associates With Impaired Insulin Secretion in Genetically Predisposed Individuals.

The Journal of clinical endocrinology and metabolism - 1 Nov 2020

Wagner Róbert, Jaghutriz Benjamin Assad, Gerst Felicia, Barroso Oquendo Morgana, Machann Jürgen, Schick Fritz, Löffler Markus W, Nadalin Silvio, Fend Falko, Königsrainer Alfred, Peter Andreas, Siegel-Axel Dorothea, Ullrich Susanne, Häring Hans-Ulrich, Fritsche Andreas, Heni Martin

Abstract excerpt

CONTEXT: Pancreatic steatosis leading to beta-cell failure might be involved in type 2 diabetes (T2D) pathogenesis. OBJECTIVE: We hypothesized that the genetic background modulates the effect of pancreatic fat on beta-cell function and investigated genotype × pancreatic fat interactions on insulin secretion. DESIGN: Two observational studies. SETTING: University hospital. PATIENTS OR PARTICIPANTS: A total of 360...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 32725157
DOI: 10.1210/clinem/dgaa435
PMCID: PMC7497818

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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