Article
The genetics of insulin resistance: Where's Waldo?
Current diabetes reports - 1 Dec 2010
Watanabe Richard M
Abstract excerpt
The physiologic hallmarks of type 2 diabetes are insulin resistance in hepatic and peripheral tissues and pancreatic β-cell dysfunction. Thus, genetic loci underlying susceptibility to type 2 diabetes are likely to map to one of these endophenotypes. Genome-wide association studies have now identified up to 38 susceptibility loci for type 2 diabetes and a number of other loci underlying variation in type 2...
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