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Article

The genetics of insulin resistance: Where's Waldo?

Current diabetes reports - 1 Dec 2010

Watanabe Richard M

Abstract excerpt

The physiologic hallmarks of type 2 diabetes are insulin resistance in hepatic and peripheral tissues and pancreatic β-cell dysfunction. Thus, genetic loci underlying susceptibility to type 2 diabetes are likely to map to one of these endophenotypes. Genome-wide association studies have now identified up to 38 susceptibility loci for type 2 diabetes and a number of other loci underlying variation in type 2...

Topics

Animals
Diabetes Mellitus, Type 2
Genetic Predisposition to Disease
Genome-Wide Association Study
Humans
Insulin Resistance

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 20820957
DOI: 10.1007/s11892-010-0143-1
PMCID: PMC3001333

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