Article
Pancreatic Steatosis as a Risk Phenotype for Pancreatic Ductal Adenocarcinoma: A Narrative Review.
Medicina (Kaunas, Lithuania) - 10 Apr 2026
Cammarata Roberto, La Vaccara Vincenzo, Bani Lucrezia, Giordano Federica, Castagliuolo Pierpaolo, Ristori Maria Vittoria, Aita Sara Elsa, Angeletti Silvia, Coppola Roberto, Caputo Damiano
Abstract excerpt
Background and Objectives: Pancreatic ductal adenocarcinoma (PDAC) is one of the leading causes of cancer-related mortality, largely due to late-stage diagnosis and the absence of effective population-based screening. Intrapancreatic fat deposition (IPFD) has emerged as a potential risk phenotype. This narrative review critically appraises the clinical, metabolic, epidemiologic, and mechanistic evidence linking...
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