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Article

Molecular margins in head and neck cancer: Current techniques and future directions.

Oral oncology - 1 Nov 2020

Stepan Katelyn O, Li Michael M, Kang Stephen Y, Puram Sidharth V

Abstract excerpt

Complete tumor extirpation with clear surgical margins remains a central tenet of oncologic head and neck surgery. Rates of locoregional recurrence and survival are both significantly worse when clear margins are unable to be obtained. Current clinical practice relies on the use of frozen sections intra-operatively, followed by traditional histopathologic analysis post-operatively to assess the surgical margin....

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Identifiers

PMID: 32702629
DOI: 10.1016/j.oraloncology.2020.104893
PMCID: PMC8131031

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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