Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Correlation of gene methylation in surgical margin imprints with locoregional recurrence in head and neck squamous cell carcinoma.

Cancer - 15 Jun 2015

Hayashi Masamichi, Wu Gaosong, Roh Jong-Lyel, Chang Xiaofei, Li Xiufeng, Ahn Julie, Goldsmith Marla, Khan Zubair, Bishop Justin, Zhang Zhe, Zhou Xian Chong, Richmon Jeremy, Agrawal Nishant, Koch Wayne M

Abstract excerpt

BACKGROUND: Securing negative surgical margins is a critical goal for head and neck surgery. Local recurrence develops even in some patients who have histologically negative surgical margins. Minimal residual tumor cells may lead to locoregional recurrence despite clear histologic margins reported at the time of resection of head and neck squamous cell carcinoma (HNSCC). To identify subclinical residual disease,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomarkers, Tumor
Share to Carcinoma, Squamous Cell

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Methylation

Share to DNA, Neoplasm

Share to Head and Neck Neoplasms

Share to Neoplasm Recurrence, Local

Share to Neoplasm, Residual

Share to Squamous Cell Carcinoma of Head and Neck

Source

Open in PubMed Open full text

Identifiers

PMID: 25773145
DOI: 10.1002/cncr.29303
PMCID: PMC4457542

Genes

EDNRB
HOXA9
DCC
NID2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Correlation of gene methylation in surgical margin imprints with locoregional recurrence in head and neck squamous cell carcinoma.PMID 25773145Read ↗

Molecular margins in head and neck cancer: Current techniques and future directions.Semantic proximity Read ↗

DNA methylation profiling to predict recurrence risk in meningioma: development and validation of a nomogram to optimize clinical managementSemantic proximity Read ↗

Early Postoperative Minimal Residual Disease Detection with MAESTRO Is Associated with Recurrence and Worse Survival in Patients with Head and Neck Cancer.Semantic proximity Read ↗

Molecular diagnosis of surgical margins and local recurrence in head and neck cancer patients: a prospective study.Semantic proximity Read ↗

Postoperative Lymph is a Proximal Source of ctDNA for Detection of Recurrence in HPV-independent Head and Neck CancerSemantic proximity Read ↗

Immediate postoperative minimal residual disease detection with MAESTRO predicts recurrence and survival in head and neck cancer patients treated with surgerySemantic proximity Read ↗

Transcriptomic Biomarker Signatures for Discrimination of Oral Cancer Surgical MarginsSemantic proximity Read ↗

p53 mutations in deep tissues are more strongly associated with recurrence than mutation-positive mucosal margins.Semantic proximity Read ↗

Aberrant DNA methylation of the p16, APC, MGMT, TIMP3 and CDH1 gene promoters in tumours and the surgical margins of patients with oral cavity cancerSemantic proximity Read ↗

Molecular assessment of histopathological staging in squamous-cell carcinoma of the head and neck.Semantic proximity Read ↗

Tissue RNA Sequencing Reveals Novel Biomarkers Associated with Postoperative Keloid RecurrenceSemantic proximity Read ↗

The Ligamp TP53 Assay for Detection of Minimal Residual Disease in Head and Neck Squamous Cell Carcinoma Surgical MarginsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.