Article
Premature aging and predisposition to cancers caused by mutations in RecQ family helicases.
Annals of the New York Academy of Sciences - 1 Apr 2001
Furuichi Y
Abstract excerpt
DNA helicases, because they unwind duplex DNA, have important roles in cellular DNA events such as replication, recombination, repair, and transcription. Multiple DNA helicase families with seven consensus motifs have been found, and members within each helicase family also share sequence homologies between motifs. The RecQ helicase family includes helicases that have extensive amino acid sequence homologies to...
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