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Article

Controlling the SARS-CoV-2 spike glycoprotein conformation.

Nature structural & molecular biology - 1 Oct 2020

Henderson Rory, Edwards Robert J, Mansouri Katayoun, Janowska Katarzyna, Stalls Victoria, Gobeil Sophie M C, Kopp Megan, Li Dapeng, Parks Rob, Hsu Allen L, Borgnia Mario J, Haynes Barton F, Acharya Priyamvada

Abstract excerpt

The coronavirus (CoV) spike (S) protein, involved in viral-host cell fusion, is the primary immunogenic target for virus neutralization and the current focus of many vaccine design efforts. The highly flexible S-protein, with its mobile domains, presents a moving target to the immune system. Here, to better understand S-protein mobility, we implemented a structure-based vector analysis of available β-CoV...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32699321
DOI: 10.1038/s41594-020-0479-4
PMCID: PMC8581954

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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