Article

Dynamic Interactions of Fully Glycosylated SARS-CoV-2 Spike Protein with Various Antibodies

2021-05-11

Abstract excerpt

<h4>ABSTRACT</h4> The spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) presents a public health crisis, and the vaccines that can induce highly potent neutralizing antibodies are essential for ending the pandemic. The spike (S) protein on the viral envelope mediates human angiotensin-converting enzyme 2 (ACE2) binding and thus is the target of a variety of neutralizing antibodies. In this wo...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 0d390275-84aa-5c1b-a154-6d7efbc17e5b
DOI: 10.1101/2021.05.10.443519

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Dynamic Interactions of Fully Glycosylated SARS-CoV-2 Spike Protein with Various AntibodiesDOI 10.1101/2021.05.10.443519Read

Dynamic Interactions of Fully Glycosylated SARS-CoV-2 Spike Protein with Various Antibodies.Semantic proximity Read

Beyond Shielding: The Roles of Glycans in SARS-CoV-2 Spike ProteinSemantic proximity Read

Virus-Receptor Interactions of Glycosylated SARS-CoV-2 Spike and Human ACE2 ReceptorSemantic proximity Read

Modeling Coronavirus Spike Protein Dynamics: Implications for Immunogenicity and Immune EscapeSemantic proximity Read

Structural basis of Omicron immune evasion: A comparative computational study of Spike protein-Antibody interactionSemantic proximity Read

Structural remodeling of SARS-CoV-2 spike protein glycans reveals the regulatory roles in receptor-binding affinitySemantic proximity Read

Computational Study of Antibody Binding to SARS-CoV-2 VariantsSemantic proximity Read

Virus-Receptor Interactions of Glycosylated SARS-CoV-2 Spike and Human Ace2 ReceptorSemantic proximity Read

Structural remodeling of SARS-CoV-2 spike protein glycans reveals the regulatory roles in receptor binding affinitySemantic proximity Read

Omicron-included mutation-induced changes in epitopes of SARS-CoV-2 spike protein and effectiveness assessments of current antibodiesSemantic proximity Read

Role of N-Glycosylation in SARS-CoV-2 Spike Glycoprotein Conformational Dynamics, Structure, and Function.Semantic proximity Read

Mapping the allosteric effects that define functional activity of SARS-CoV-2 specific antibodiesSemantic proximity Read