Article
SARS-CoV-2 Omicron variations reveal mechanisms controlling cell entry dynamics and antibody neutralization
2 Dec 2024
Abstract excerpt
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is adapting to continuous presence in humans. Transitions to endemic infection patterns are associated with changes in the spike (S) proteins that direct virus-cell entry. These changes generate antigenic drift and thereby allow virus maintenance in the face of prevalent human antiviral antibodies. These changes also fine tune virus-cell entry dynamics...
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