Article
SNP-HLA Reference Consortium (SHLARC): HLA and SNP data sharing for promoting MHC-centric analyses in genomics.
Genetic epidemiology - 1 Oct 2020
Vince Nicolas, Douillard Venceslas, Geffard Estelle, Meyer Diogo, Castelli Erick C, Mack Steven J, Limou Sophie, Gourraud Pierre-Antoine
Abstract excerpt
Genome-wide associations studies have repeatedly identified the major histocompatibility complex genomic region (6p21.3) as key in immune pathologies. Researchers have also aimed to extend the biological interpretation of associations by focusing directly on human leukocyte antigen (HLA) polymorphisms and their combination as haplotypes. To circumvent the effort and high costs of HLA typing, statistical solutions...
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