Article
Understanding the Mechanisms by Which Epigenetic Modifiers Avert Therapy Resistance in Cancer
24 Jun 2020
Abstract excerpt
The development of resistance to anti-cancer therapeutics remains one of the core issues preventing the improvement of survival rates in cancer. Therapy resistance can arise in a multitude of ways, including the accumulation of epigenetic alterations in cancer cells. By remodeling DNA methylation patterns or modifying histone proteins during oncogenesis, cancer cells reorient their epigenomic landscapes in order...
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