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The pharmacoepigenetic paradigm in cancer treatment

24 Apr 2024

Abstract excerpt

Epigenetic modifications, characterized by changes in gene expression without altering the DNA sequence, play a crucial role in the development and progression of cancer by significantly influencing gene activity and cellular function. This insight has led to the development of a novel class of therapeutic agents, known as epigenetic drugs. These drugs, including histone deacetylase inhibitors, histone...

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PMID: 38720770
DOI: 10.3389/fphar.2024.1381168

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