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DNA Methylation: From Cancer Biology to Clinical Perspectives

20 Dec 2022

Abstract excerpt

DNA methylation plays an important role in the silence of tissue-specific genes to prevent them from being expressed in the wrong tissue. Aberrant DNA methylation (genome-wide hypomethylation and site-specific hypermethylation) are observed in many types of cancer. DNA methylation patterns are established and maintained through the combined actions of methyltransferase and demethylase, such as DNA...

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PMID: 36624943
DOI: 10.31083/j.fbl2712326

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