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Epigenetics and Oncology

11 Mar 2014

Abstract excerpt

Epigenetic modifications play a critical role in the development of pediatric and adult cancers, contributing to the cumulative changes observed as normal cells undergo malignant transformation. These modifications have been studied to develop epigenome-targeted therapies and new diagnostic tools. The U.S. Food and Drug Administration has approved four epigenome-targeted anticancer drugs. Two are drugs that...

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PMID: 24619798
DOI: 10.1002/phar.1408

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