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Article

The cancer epigenome: Concepts, challenges, and therapeutic opportunities.

Science (New York, N.Y.) - 17 Mar 2017

Dawson Mark A

Abstract excerpt

Cancer biology is profoundly influenced by changes in the epigenome. Because the dynamic plasticity of the epigenome lends itself well to therapeutic manipulation, the past few years have witnessed an unprecedented investment in the development, characterization, and translation of targeted epigenetic therapies. In this review, I provide a broad context for recent developments that offer a greater understanding...

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Share to Chromatin Assembly and Disassembly
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28302822
DOI: 10.1126/science.aam7304

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