Epigenome: a new target in cancer therapy.

Abstract excerpt

Until short time ago we considered cancer as the result of genetic mutations, but recent studies have shown that genetic mutations are not the only responsible for tumorigenesis. Although the genome contains all the information needed to encode the entire set of proteins, the expression of this information is regulated by the epigenome. Hypermethylation is one of the best known epigenetic events in mammalian...

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