Article
Next-generation sequencing of 11 HLA loci in a large dengue vaccine cohort from the Philippines.
Human immunology - 1 Aug 2020
Geretz Aviva, Cofer Lauryn, Ehrenberg Philip K, Currier Jeffrey R, Yoon In-Kyu, Alera Maria T P, Jarman Richard, Rothman Alan L, Thomas Rasmi
Abstract excerpt
HLA genotyping by next-generation sequencing (NGS) has evolved with significant advancements in the last decade. Here we describe full-length HLA genotyping of 11 loci in 612 individuals comprising a dengue vaccine cohort from Cebu province in the Philippines. The multi-locus individual tagging NGS (MIT-NGS) method that we developed initially for genotyping 4-6 loci in one MiSeq run was expanded to 11 loci...
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