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Article

Next-generation sequencing of HLA: validation and identification of new polymorphisms in a Brazilian population.

HLA - 1 Jul 2020

Fabreti-Oliveira Raquel A, Oliveira Cintia K F, Vale Eliane M G, Nascimento Evaldo

Abstract excerpt

BACKGROUND: Next-generation sequencing (NGS) is the most modern sequencing technique that has revolutionized HLA typing, providing high-resolution results with low ambiguity rates. This study aimed to show the experiences and challenges of an HLA laboratory in the validation process of the NGS methodology for HLA typing and show the use of this method for the study of HLA genetic diversity. METHODS: We used 115...

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PMID: 32222028
DOI: 10.1111/tan.13880

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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