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Full-Length Next-Generation Sequencing of 11 HLA Loci of More Than 1000 Individuals From Clinical Cohorts in East and West Africa.

HLA - 1 Jul 2026

Rosario Yvonne V, Geretz Aviva, Iyer Lakshmi Rani, Ehrenberg Philip K, Tyson Alýa, Kibuuka Hannah, Wabwire-Mangen Fred, Maganga Lucas, Tiamiyu Abdulwasiu, Maswai Jonah, Kosgei Josphat, Sawe Frederick, Matyas Gary R, Robb Merlin L, Ake Julie A, Thomas Rasmi

Abstract excerpt

HLA loci have been implicated in several diseases, including HIV-1, from different world populations. It is necessary to characterise HLA allele variation at the population level prior to investigating associations linked to human diseases. In global databases, limited high-resolution HLA allele types generated by next-generation sequencing (NGS) have been described for populations from African countries. We...

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PMID: 42362493
DOI: 10.1111/tan.70814
PMCID: PMC13309289

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