Unveiling the pathophysiology of restless legs syndrome through transcriptome analysis

Abstract excerpt

The aim of this study was to analyze signaling pathways associated with differentially expressed messenger RNAs in people with restless legs syndrome (RLS). Seventeen RLS patients and 18 controls were enrolled. Coding RNA expression profiling of 12,857 gene transcripts by next-generation sequencing was performed. Enrichment analysis by pathfindR tool was carried-out, with p-adjusted ≤0.001 and fold-change ≥2.5....

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Dysphagia Assessment and Management
• Share to Parkinson's Disease Mechanisms and Treatments
• Share to Restless Legs Syndrome Research