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Article

Genome-wide meta-analysis identifies genetic risk loci for mono- and polyneuropathies in 983 477 individuals.

Human molecular genetics - 23 Feb 2026

Broberg Martin, Gen Finn, Kalso Eija, Ollila Hanna M

Abstract excerpt

Peripheral neuropathies are common neurological disorders affecting sensory, autonomic, and motor nerves, with an estimated prevalence exceeding 2% in the general population. Typical symptoms include numbness and distal limb muscle weakness, resulting from somatosensory nerve damage. Here, we investigate the genetic architecture of mono- and polyneuropathies and their relationships with comorbid traits using data...

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Share to DCC gene
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 41518141
DOI: 10.1093/hmg/ddaf200
PMCID: PMC13036838

Genes

ADAMTS17
BCL11A
COL11A1
DCC
ETV1
HTR3A
LOXL4
NEGR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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