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Article

Clonal Hematopoiesis of Indeterminate Potential and Cardiovascular Health.

Cardiology clinics - 1 Feb 2025

Raddatz Michael A, Pershad Yash, Parker Alyssa C, Bick Alexander G

Abstract excerpt

Clonal hematopoiesis of indeterminate potential (CHIP) is an age-related phenomenon in which somatic mutations lead to clonal expansion of hematopoietic stem cells without the development of hematologic abnormalities. A growing body of literature demonstrates an association between CHIP and cardiovascular disease. This pathophysiology demonstrates a novel connection between global inflammation and cardiovascular...

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Identifiers

PMID: 39551555
DOI: 10.1016/j.ccl.2024.08.004
PMCID: PMC12440153

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