Cumulative impact of common genetic variants and other risk factors on colorectal cancer risk in 42,103 individuals.

doi:10.1136/gutjnl-2011-300537

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Article

Cumulative impact of common genetic variants and other risk factors on colorectal cancer risk in 42,103 individuals.

Gut - 1 Jun 2013

Dunlop Malcolm G, Tenesa Albert, Farrington Susan M, Ballereau Stephane, Brewster David H, Koessler Thibaud, Pharoah Paul, Schafmayer Clemens, Hampe Jochen, Völzke Henry, Chang-Claude Jenny, Hoffmeister Michael, Brenner Hermann, von Holst Susanna, Picelli Simone, Lindblom Annika, Jenkins Mark A, Hopper John L, Casey Graham, Duggan David, Newcomb Polly A, Abulí Anna, Bessa Xavier, Ruiz-Ponte Clara, Castellví-Bel Sergi, Niittymäki Iina, Tuupanen Sari, Karhu Auli, Aaltonen Lauri, Zanke Brent, Hudson Tom, Gallinger Steven, Barclay Ella, Martin Lynn, Gorman Maggie, Carvajal-Carmona Luis, Walther Axel, Kerr David, Lubbe Steven, Broderick Peter, Chandler Ian, Pittman Alan, Penegar Steven, Campbell Harry, Tomlinson Ian, Houlston Richard S

Abstract excerpt

OBJECTIVE: Colorectal cancer (CRC) has a substantial heritable component. Common genetic variation has been shown to contribute to CRC risk. A study was conducted in a large multi-population study to assess the feasibility of CRC risk prediction using common genetic variant data combined with oth...

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PMID: 22490517
DOI: 10.1136/gutjnl-2011-300537
PMCID: PMC5105590

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22490517-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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