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Article

Colorectal Cancer Risk Loci: Prognostic Factors for Clinical Outcomes? A Systematic Review and Meta-Analysis.

Cancer reports (Hoboken, N.J.) - 1 May 2025

Wu Chengmi, Zhou Jingyi, Wu Qian, Xu Shu, Jiang Jie, Li Sha, Chen Xuechen

Abstract excerpt

BACKGROUND: Several single nucleotide polymorphisms (SNPs) identified through genome-wide association studies (GWASs) on colorectal cancer (CRC) incidence are also shown as promising predictors of clinical outcomes in CRC patients. These genetic variants might help inform precision prognostic strategies by predicting disease progression, treatment response, and overall survival, thereby guiding more personalized...

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Identifiers

PMID: 40387276
DOI: 10.1002/cnr2.70230
PMCID: PMC12931425

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