Article
Association study of polymorphisms in the group III metabotropic glutamate receptor genes, GRM4 and GRM7, with schizophrenia.
Psychiatry research - 15 May 2009
Shibata Hiroki, Tani Ayako, Chikuhara Tomoyuki, Kikuta Rumiko, Sakai Mayumi, Ninomiya Hideaki, Tashiro Nobutada, Iwata Nakao, Ozaki Norio, Fukumaki Yasuyuki
Abstract excerpt
Based on the hypothesis that a glutamatergic dysfunction is involved in the pathophysiology of schizophrenia, we have been conducting systematic studies on the association between glutamate receptor genes and schizophrenia. Here we report association studies of schizophrenia with polymorphisms in group III metabotropic glutamate receptor genes, GRM4 and GRM7. We selected 8 and 43 common SNPs distributed in the...
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