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Article

The CSMD1 genome-wide associated schizophrenia risk variant rs10503253 affects general cognitive ability and executive function in healthy males.

Schizophrenia research - 1 Apr 2014

Koiliari Erasmia, Roussos Panos, Pasparakis Emmanouil, Lencz Todd, Malhotra Anil, Siever Larry J, Giakoumaki Stella G, Bitsios Panos

Abstract excerpt

BACKGROUND: The single-nucleotide polymorphism (SNP) rs10503253, located within the CUB and Sushi multiple domains-1 (CSMD1) gene on 8p23.2, has reached genome-wide support as a risk factor for schizophrenia. There is initial but inconclusive evidence for a role of this variant in aspects of cognition. METHODS: We investigated the neurocognitive effects of the CSMD1 rs10503253 (C/A) polymorphism in a large,...

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Identifiers

PMID: 24630139
DOI: 10.1016/j.schres.2014.02.017

Genes

CSMD1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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