Article
Polymorphisms associated with normal memory variation also affect memory impairment in schizophrenia.
Genes, brain, and behavior - 1 Jun 2011
Jablensky A, Morar B, Wiltshire S, Carter K, Dragovic M, Badcock J C, Chandler D, Peters K, Kalaydjieva L
Abstract excerpt
Neurocognitive dysfunction is a core feature of schizophrenia with particularly prominent deficits in verbal episodic memory. The molecular basis of this memory impairment is poorly understood and its relatedness to normal variation in memory performance is unclear. In this study, we explore, in a sample of cognitively impaired schizophrenia patients, the role of polymorphisms in seven genes recently reported to...
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