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Article

Evaluation of population stratification adjustment using genome-wide or exonic variants.

Genetic epidemiology - 1 Oct 2020

Chen Yuning, Peloso Gina M, Liu Ching-Ti, DeStefano Anita L, Dupuis Josée

Abstract excerpt

Population stratification may cause an inflated type-I error and spurious association when assessing the association between genetic variations with an outcome. Many genetic association studies are now using exonic variants, which captures only 1% of the genome, however, population stratification adjustments have not been evaluated in the context of exonic variants. We compare the performance of two established...

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Identifiers

PMID: 32608112
DOI: 10.1002/gepi.22332
PMCID: PMC7722041

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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