Marbled inflation from population structure in gene-based association studies with rare variants.

Abstract excerpt

Accurate genetic association studies are crucial for the detection and the validation of disease determinants. One of the main confounding factors that affect accuracy is population stratification, and great efforts have been extended for the past decade to detect and to adjust for it. We have now efficient solutions for population stratification adjustment for single-SNP (where SNP is single-nucleotide...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Case-Control Studies
• Share to Computer Simulation
• Share to Gene Frequency