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Article

Prioritization of causal genes for coronary artery disease based on cumulative evidence from experimental and in silico studies.

Scientific reports - 26 Jun 2020

Shadrina Alexandra S, Shashkova Tatiana I, Torgasheva Anna A, Sharapov Sodbo Z, Klarić Lucija, Pakhomov Eugene D, Alexeev Dmitry G, Wilson James F, Tsepilov Yakov A, Joshi Peter K, Aulchenko Yurii S

Abstract excerpt

Genome-wide association studies have led to a significant progress in identification of genomic loci affecting coronary artery disease (CAD) risk. However, revealing the causal genes responsible for the observed associations is challenging. In the present study, we aimed to prioritize CAD-relevant genes based on cumulative evidence from the published studies and our own study of colocalization between eQTLs and...

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Identifiers

PMID: 32591598
DOI: 10.1038/s41598-020-67001-w
PMCID: PMC7320185

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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