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Article

Network-Based Identification and Prioritization of Key Regulators of Coronary Artery Disease Loci.

Arteriosclerosis, thrombosis, and vascular biology - 1 May 2016

Zhao Yuqi, Chen Jing, Freudenberg Johannes M, Meng Qingying, Rajpal Deepak K, Yang Xia

Abstract excerpt

OBJECTIVE: Recent genome-wide association studies of coronary artery disease (CAD) have revealed 58 genome-wide significant and 148 suggestive genetic loci. However, the molecular mechanisms through which they contribute to CAD and the clinical implications of these findings remain largely unknown. We aim to retrieve gene subnetworks of the 206 CAD loci and identify and prioritize candidate regulators to better...

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Identifiers

PMID: 26966275
DOI: 10.1161/ATVBAHA.115.306725
PMCID: PMC5576868

Genes

CAD
LUM
STAT3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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