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Article

Effects of a postnatal Atrx conditional knockout in neurons on autism-like behaviours in male and female mice.

Journal of neurodevelopmental disorders - 24 Jun 2020

Martin-Kenny Nicole, Bérubé Nathalie G

Abstract excerpt

BACKGROUND: Alpha-thalassemia/mental retardation, X-linked, or ATRX, is an autism susceptibility gene that encodes a chromatin remodeler. Mutations of ATRX result in the ATR-X intellectual disability syndrome and have been identified in autism spectrum disorder (ASD) patients. The mechanisms by which ATRX mutations lead to autism and autistic-like behaviours are not yet known. To address this question, we...

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Identifiers

PMID: 32580781
DOI: 10.1186/s11689-020-09319-0
PMCID: PMC7315487

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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