Article

Effects of a postnatal <i>Atrx</i> conditional knockout in neurons on autism-like behaviours in male and female mice

2020-02-07

Abstract excerpt

<h4>Background</h4> Alpha-thalassemia/mental retardation, X-linked, or ATRX , is an autism susceptibility gene that encodes a chromatin remodeler. Mutations of ATRX result in the ATR-X intellectual disability syndrome and have been identified in autism spectrum disorder (ASD) patients. The mechanisms by which ATRX mutations lead to autism and autistic-like behaviours are not yet known. To address this question...

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Literature Corpus work: e577639b-8386-5ee0-8a61-106f2baf2216
DOI: 10.1101/2020.02.05.936260

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