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Article

Using iPSC-Based Models to Understand the Signaling and Cellular Phenotypes in Idiopathic Autism and 16p11.2 Derived Neurons.

Advances in neurobiology - 1 Jan 2020

Turkalj Luka, Mehta Monal, Matteson Paul, Prem Smrithi, Williams Madeline, Connacher Robert J, DiCicco-Bloom Emanuel, Millonig James H

Abstract excerpt

Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder that is remarkably heterogeneous at the clinical, neurobiological, and genetic levels. ASD can also affect language, a uniquely human capability, and is caused by abnormalities in brain development. Traditionally obtaining biologically relevant human cells to study ASD has been extremely difficult, but new technologies including iPSC-derived neurons...

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PMID: 32578145
DOI: 10.1007/978-3-030-45493-7_4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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