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Article

Idiopathic Autism: Cellular and Molecular Phenotypes in Pluripotent Stem Cell-Derived Neurons.

Molecular neurobiology - 1 Aug 2017

Liu Xiaozhuo, Campanac Emilie, Cheung Hoi-Hung, Ziats Mark N, Canterel-Thouennon Lucile, Raygada Margarita, Baxendale Vanessa, Pang Alan Lap-Yin, Yang Lu, Swedo Susan, Thurm Audrey, Lee Tin-Lap, Fung Kwok-Pui, Chan Wai-Yee, Hoffman Dax A, Rennert Owen M

Abstract excerpt

Autism spectrum disorder is a complex neurodevelopmental disorder whose pathophysiology remains elusive as a consequence of the unavailability for study of patient brain neurons; this deficit may potentially be circumvented by neural differentiation of induced pluripotent stem cells. Rare syndromes with single gene mutations and autistic symptoms have significantly advanced the molecular and cellular...

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Identifiers

PMID: 27356918
DOI: 10.1007/s12035-016-9961-8
PMCID: PMC5199629

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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