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Generation and characterization of human induced pluripotent stem cell lines from patients with autism spectrum disorder and SCN2A variants

2024-07-30

Abstract excerpt

<title>Abstract</title> <p>Autism spectrum disorders (ASD) comprise a group of complex neurodevelopmental disorders that affect communication and social interactions. Over a thousand genes have been associated with ASD, with SCN2A standing out due to its critical role in neuronal function and development. Induced pluripotent stem cells (iPSCs) derived from individuals with ASD have become invaluable in vitro mode...

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Literature Corpus work
d0412c84-f826-5d73-9ead-1c6ef1f9345b
DOI
10.21203/rs.3.rs-4676288/v1
Open publication

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Generation and characterization of human induced pluripotent stem cell lines from patients with autism spectrum disorder and SCN2A variantsDOI 10.21203/rs.3.rs-4676288/v1
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