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Article

Amyloid precursor protein-b facilitates cell adhesion during early development in zebrafish.

Scientific reports - 23 Jun 2020

Banote Rakesh Kumar, Chebli Jasmine, Şatır Tuğçe Munise, Varshney Gaurav K, Camacho Rafael, Ledin Johan, Burgess Shawn M, Abramsson Alexandra, Zetterberg Henrik

Abstract excerpt

Understanding the biological function of amyloid beta (Aβ) precursor protein (APP) beyond its role in Alzheimer's disease is emerging. Yet, its function during embryonic development is poorly understood. The zebrafish APP orthologue, Appb, is strongly expressed during early development but thus far has only been studied via morpholino-mediated knockdown. Zebrafish enables analysis of cellular processes in an...

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Identifiers

PMID: 32576936
DOI: 10.1038/s41598-020-66584-8
PMCID: PMC7311384

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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