Article
Amyloid precursor protein is required for convergent-extension movements during Zebrafish development.
Developmental biology - 1 Nov 2009
Joshi Powrnima, Liang Jennifer O, DiMonte Kristine, Sullivan John, Pimplikar Sanjay W
Abstract excerpt
Amyloid precursor protein (APP) has been a focus of intense investigation because of its role in Alzheimer's disease (AD), however, its biological function remains uncertain. Loss of APP and APP-like proteins results in postnatal lethality in mice, suggesting a role during embryogenesis. Here we...
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