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Amyloid precursor protein-b facilitates cell adhesion during early development in zebrafish

2019-10-05

Abstract excerpt

Understanding the biological function of amyloid beta (Aβ) precursor protein (APP) beyond its role in Alzheimer’s disease is emerging. Yet, its function during embryonic development is poorly understood. The zebrafish APP homologue, Appb, is strongly expressed during early development but thus far has only been studied via morpholino-mediated knockdown. Zebrafish enables analysis of cellular processes in an ontoge...

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Literature Corpus work
6f5e250b-443b-5391-bea6-d55b23fbe1d7
DOI
10.1101/795187
Open publication

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Amyloid precursor protein-b facilitates cell adhesion during early development in zebrafishDOI 10.1101/795187
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